Figure 3.

Effects of sodium butyrate, sodium acetate, and sodium propionate on vascular tone in anesthetized zebrafish larvae. A: 2.2 µM sodium butyrate produced a significant decrease in the cross-sectional width of the dorsal aorta (DA) at 60 min. B: red dotted lines mark the outline of the DA at baseline (0 min, left) and at 60 min (right) following exposure to sodium butyrate. Scale bar in orange = 200 µm. C and D: 27.4 µM acetate (C) and 1.7 µM propionate (D) produced no change. Data are presented as means ± SE and calculated as %Baseline (0 min). n = 5–8/treatment group. Repeated-measures one-way ANOVA with a Dunnett’s post hoc test; *P < 0.05.