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Schematic depiction of the DG laminin receptor and some of its interactive ligands. Some of the extracellular HSPG ligands that interact with αDG are shown including, perlecan, agrin, pikachurin and eyes-shut. Biosynthetic enzymes responsible for the glycosylation of the α-dystroglycan matriglycan component are also shown emphasizing the unique glycosylation of DG which conveys its unique interactive properties with ECM components.
