Table 1.

Examples of radiotherapy-induced pain syndromes and associated symptoms.

Acute phase radiation-related pain	Symptoms	Late phase radiation-related pain	Symptoms
Enteritis	Abdominal pain Diarrhoea Vomiting	Radiation fibrosis syndrome	Dependent on area affected -dystonia -muscle spasm -lymphoedema
Oesophagitis	Dysphagia Vomiting Reflux Cough	Osteoradionecrosis of jaw	Pain Trismus Orocutaneous fistula Non-healing ulcers
Oral mucositis	Oral Pain Ulcers Dysgeusia Weight loss (secondary decreased oral intake)	Oesophageal stricture	Reflux Bitter/acid taste Hiccups Dysphagia Weight loss
Proctitis	Tenesmus Pus/blood in stool Diarrhoea Abdominal pain	Dyspareunia	Painful intercourse
Dermatitis	Colour changes Swelling Desquamation/skin breakdown	Lower GI tract stricture	Painful defaecation (anal stricture) Bowel obstruction
		Peripheral neuropathy	Gain or loss of function neuropathic symptoms