Table 3.
Study population demographics their associations with chronic placental inflammation pathology.
| Males | Females | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| No Pathology (N=255) N (%) | Chronic Placental Inflammation Present(N=257) N (%) | P-value* | No Pathology (N=287) N (%) | Chronic Placental Inflammation Present (N=218) N (%) | P-value* | |
|
| ||||||
| Maternal Age (years) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | ||
| 29.9 (6.1) | 29.9 (6.5) | 29.6 (6.4) | 30.4 (6.3) | |||
| <25 | 58 (23) | 67 (26) | 0.83 | 76 (27) | 46 (21) | 0.47 |
| 25–32 | 109 (43) | 103 (40) | 127 (44) | 100 (46) | ||
| 33–40 | 90 (31) | 78 (30) | 73(25) | 60 (27) | ||
| 41+ | 8 (3) | 9 (4) | 11 (4) | 12 (6) | ||
| Placental weight (g) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | ||
| 492.3 (89.9) | 487.0 (98.6) | 502.6 (93.0) | 472.5 (97.2) | |||
| <25th | 59 (23) | 70 (27) | 0.70 | 57 (20) | 72 (33) | 0.008 |
| 25th - 50th | 80 (31) | 75(29) | 76 (26) | 52 (24) | ||
| 51st - 75 th | 69 (27) | 63 (25) | 92 (32) | 59 (27) | ||
| 76th + | 47 (19) | 49 (19) | 62 (22) | 35 (16) | ||
| Birth weight (g) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | ||
| 3394.2 (420.9) | 3299.5 (469.9) | 3251.7 (432.0) | 3188.2 (469.7) | |||
| <25th | 60 (23) | 79 (31) | 0.035 | 63 (22) | 71 (33) | 0.032 |
| 25th - 50th | 73 (29) | 82 (32) | 96 (33) | 57 (26) | ||
| 51st - 75 th | 62 (24) | 59 (23) | 80 (28) | 50 (23) | ||
| 76th + | 60 (24) | 37 (14) | 48 (17) | 40 (18) | ||
| Gestational age (weeks) | Mean (SD) | Mean (SD) | 0.97 | Mean (SD) | Mean (SD) | 0.63 |
| 38.99 (1.1) | 38.99 (1.1) | 38.96 (1.1) | 39.0 (1.1) | |||
Chronic Placental Inflammation Present defined as the presence of at least one of the following: CD, CV, PCs, or Anch.
No Pathology defined as the absence of all placental histopathology types: acute inflammation in maternal or fetal tissues, chronic placental inflammation, fetal vascular pathology or malperfusion, maternal uteroplacental vascular malperfusion, and villous dysmaturity.
*
P-values reported for chi-square test of independence or t-test (gestational age)