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. Author manuscript; available in PMC: 2025 Sep 1.
Published in final edited form as: Adv Healthc Mater. 2024 May 21;13(22):e2400457. doi: 10.1002/adhm.202400457

Figure 1. Schematic illustration of the hydrogel formulations used in this study.

Figure 1.

The formulations contain a temperature-responsive hydrogel, poloxamer 407 (P407), a broad-spectrum antibiotic, ciprofloxacin, and different chemical permeation enhancers (CPEs), including methyl laurate (ML), for the local, non-invasive treatment of acute otitis media (AOM).