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. 2024 Sep 2;13(5):tfae141. doi: 10.1093/toxres/tfae141

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Fig. 3 — Photomicrograph of liver of control group a) and AN B) showing normal architecture of portal area with polyhedral shaped hepatocytes arranged in cord-like pattern (white arrow heads) and separated by blood sinusoids (black arrow heads) contained Kupffer cells (thin arrows) in addition to intact portal vein (thick arrow) Stain H&E, bar = 50 μm. Photomicrograph of liver of gentamicin treated group C) showing severe congestion of portal vein (thick black arrow), and hepatic sinusoids (black arrow heads) besides fibrosis of portal area (white arrows), hypertrophy of bile duct (white arrow heads) hepatocellular necrosis (asterisk) and infiltration of inflammatory cells (thin black arrow). Stain H&E, bar = 50 μm. Photomicrograph of liver of gentamicin plus AN treated group D) showing moderate congestion of hepatic sinusoids (arrow heads) and small areas of vacuolar degenerative changes in hepatocytes (arrows). Stain H&E, bar = 50 μm.