Table 2.

Average JSD (k = 20) and Spearman’s correlation coefficient of across multiple platform benchmarking experiments

Method	Mean of three mouse embryos		Human breast
	JSD	Spearman’s ρ	JSD	Spearman’s ρ
Ours	0.305∗	0.283∗	0.306∗	0.103
SageNet	0.359	0.198	0.369	0.172∗
CeLEry	0.577	0.156	0.465	0.077
CytoSpace	0.568	0.099	0.444	0.005
NovoSpaRc	0.579	0.066	0.393	0.044
Tangram	0.614	0.053	0.485	0.007

Spearman’s ρ denotes Spearman’s correlation coefficient.

Asterisks denote the best performed method for each metric.