Changes in patterns of recurrent aberrations over time
(A) The relative frequency of the six most common abnormalities in the WiCell dataset over time.
(B) The relative frequency of the four most common abnormalities in the CSCB dataset over time.
(C) The proportion of abnormal karyotypes containing one of the six most common abnormalities in the WiCell dataset sampled in the year 2009 versus the year 2021. ns, non-significant; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001; Fisher’s exact test.
(D) The proportion of abnormal karyotypes containing one of the four most common abnormalities in the CSCB dataset sampled in 2002–2007 versus 2017–2019 (several years are pooled together due to relatively low n numbers in this dataset). ns, non-significant; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗∗p < 0.0001; Fisher’s exact test.