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. 2024 Jul 11;19(8):1043–1047. doi: 10.1016/j.stemcr.2024.06.004

Table 1.

The 30 most frequent HLA haplotypes in the Saudi population, their frequencies, estimated coverage, and the corresponding discovery sample size

Haplotype n Frequency Cumulative population coverage Discovery sample size (IC method) Discovery sample size (standard method)
A∗02∼B∗50∼DRB1∗07 3,257 0.035820445 0.070357785 1,163.2 779.4
A∗02∼B∗51∼DRB1∗04 1,710 0.018817209 0.106290035 2,214.3 2,824.2
A∗26∼B∗08∼DRB1∗03 1,256 0.01381056 0.13221127 3,017.0 5,243.0
A∗23∼B∗50∼DRB1∗07 1,168 0.01284866 0.155984567 3,242.9 6,057.4
A∗02∼B∗07∼DRB1∗15 1,073 0.011789139 0.177507021 3,534.3 7,195.1
A∗01∼B∗41∼DRB1∗07 989 0.010885212 0.197132434 3,827.8 8,439.7
A∗31∼B∗51∼DRB1∗13 897 0.009864418 0.214712733 4,223.9 10,276.8
A∗24∼B∗08∼DRB1∗03 886 0.00973965 0.231879733 4,278.0 10,541.8
A∗68∼B∗08∼DRB1∗03 789 0.008673389 0.247007651 4,804.0 13,293.0
A∗33∼B∗14∼DRB1∗01 684 0.007517493 0.259997767 5,542.6 17,695.1
A∗02∼B∗51∼DRB1∗13 631 0.006935427 0.271881844 6,007.8 20,790.0
A∗02∼B∗51∼DRB1∗15 619 0.00678727 0.28341891 6,138.9 21,707.5
A∗01∼B∗73∼DRB1∗10 582 0.006398224 0.294210309 6,512.2 24,427.6
A∗02∼B∗07∼DRB1∗03 579 0.00635411 0.304846275 6,557.4 24,768.0
A∗11∼B∗52∼DRB1∗15 564 0.006205572 0.315155666 6,714.4 25,967.9
A∗68∼B∗50∼DRB1∗07 562 0.006184673 0.325353708 6,737.1 26,143.7
A∗03∼B∗50∼DRB1∗07 555 0.006106359 0.335347563 6,823.5 26,818.6
A∗33∼B∗58∼DRB1∗03 529 0.005815561 0.344796156 7,164.7 29,567.6
A∗31∼B∗50∼DRB1∗07 512 0.005623392 0.353868204 7,409.5 31,623.0
A∗30∼B∗42∼DRB1∗03 512 0.005620087 0.362871732 7,413.9 31,660.2
A∗24∼B∗35∼DRB1∗11 489 0.005374934 0.371423421 7,752.0 34,614.2
A∗31∼B∗15∼DRB1∗13 479 0.005264996 0.379744176 7,913.9 36,074.8
A∗30∼B∗53∼DRB1∗13 457 0.005026816 0.387636778 8,288.9 39,574.4
A∗24∼B∗15∼DRB1∗13 457 0.00502551 0.395476811 8,291.0 39,595.0
A∗02∼B∗51∼DRB1∗16 430 0.004726393 0.402804117 8,815.7 44,765.2
A∗68∼B∗07∼DRB1∗04 426 0.004685168 0.410023416 8,893.3 45,556.4
A∗02∼B∗58∼DRB1∗03 423 0.004675942 0.417184728 8,910.9 45,736.4
A∗30∼B∗13∼DRB1∗07 423 0.004654791 0.424270214 8,951.4 46,153.0
A∗68∼B∗51∼DRB1∗11 414 0.004557838 0.431166128 9,141.8 48,137.4
A∗01∼B∗52∼DRB1∗15 413 0.004550811 0.438009959 9,155.9 48,286.1

Complete list can be found in Table S1. n denotes the number of individuals carrying the corresponding haplotype in the cohort (Alfraih et al., 2021). IC stands for inbreeding coefficient method.