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. 2024 Aug 1;19(8):1189–1204. doi: 10.1016/j.stemcr.2024.07.003

Figure 2.

Figure 2

scRNA-seq of E14.5 iHSCs and iMPPs

(A) Gating strategy used to purify E14.5 FL LSK subsets.

(B) Heatmap of 100 most variable genes for each LSK subtype.

(C) Gene Ontology (GO) term enrichment analysis for differentially expressed genes for iMPP3 versus iMPP4 (i). (ii) Genes in significant GO terms.

(D) GO term analysis for iMPP2 versus iMPP4 (i). (ii) Genes in significant GO terms.

(E) GO term analysis for iMPP2 versus iMPP3 (i). (ii) Genes in significant GO terms. Lymph, lymphoid; Lymph/Mye, lymphoid and myeloid; Mye, myeloid; Mk/Ery, megakaryocyte and erythroid; Mye/Mk/Ery, myeloid, megakaryocyte and erythroid.