Table 3. Clinicohistopathological correlation of biomarker expressions.
p53: Tumor protein p53; EGFR: estimated glomerular filtration rate; CK20: cytokeratin 20
| Biomarker | Histological Subtype | p-value |
| p53 | ||
| -Urothelial carcinoma | Positive: 105 (73.9) | <0.001 |
| Negative: 37 (26.1) | ||
| -Squamous cell carcinoma | Positive: 12 (50.0) | 0.021 |
| Negative: 12 (50.0) | ||
| Ki-67 | ||
| -Urothelial carcinoma | High: 96 (67.6) | <0.001 |
| Low: 46 (32.4) | ||
| -Squamous cell carcinoma | High: 20 (83.3) | 0.005 |
| Low: 4 (16.7) | ||
| EGFR | ||
| -Urothelial carcinoma | Overexpression: 84 (59.2) | <0.001 |
| Normal expression: 58 (40.8) | ||
| -Squamous cell carcinoma | Overexpression: 10 (41.7) | 0.042 |
| Normal expression: 14 (58.3) | ||
| CK20 | ||
| -Urothelial carcinoma | Positive: 120 (84.5) | <0.001 |
| Negative: 22 (15.5) | ||
| -Squamous cell carcinoma | Positive: 10 (41.7) | 0.018 |
| Negative: 14 (58.3) | ||