Table 4. Associations between clinical characteristics and ESBL-/MBL-producing isolates.
ESBL, extended-spectrum β-lactamase; MBL, metallo-β-lactamase
| Clinical characteristic | ESBL-producing isolates (n = 36) | MBL-producing isolates (n = 21) | p-value |
| Age (years) | Mean: 59.2 ± 8.3 | 57.8 ± 9.7 | 0.512 |
| Gender (male/female) | 18/18 | 10/11 | 0.764 |
| Duration of diabetes (years) | 13.5 ± 3.6 | 12.2 ± 4.1 | 0.279 |
| Previous antibiotic exposure (yes/no) | 25/11 | 14/7 | 0.432 |
| Comorbidities (yes/no) | 32/4 | 18/3 | 0.021 |
| Size of foot ulcers (cm²) | 5.8 ± 2.3 | 5.1 ± 2.2 | 0.342 |
| Depth of foot ulcers (cm) | 1.3 ± 0.4 | 1.2 ± 0.5 | 0.287 |
| Presence of necrotic tissue (%) | 47.2 | 38.1 | 0.219 |
| Inflammation (%) | 82.1 | 74.3 | 0.187 |
| Cellulitis (%) | 37.8 | 29.6 | 0.204 |