TABLE 3.

The results of pooled ORs, test of heterogeneity and Egger’s test for publication bias in the four genotype models of VDR gene polymorphisms in the meta-analysis.

Polymorphism	No. of studies	Case/Control	Test of association			Test of heterogeneity		Egger’s test for publication bias
			OR	95%CI	p-value	I 2 (%)	p-value	T	p-value
FokI f vs. F	22	3052/3243	1.235	(1.035–1.475)	0.019	82.5	<0.001	0.98	0.337
ff + Ff vs. FF	22	3052/3243	1.275	(0.997–1.632)	0.053	79.0	<0.001	0.47	0.644
ff vs. Ff + FF	22	3052/3243	1.317	(1.005–1.727)	0.046	71.1	<0.001	0.31	0.756
ff vs. FF	22	3052/3243	1.427	(0.994–2.048)	0.054	79.2	<0.001	0.64	0.527
BsmI b vs. B	15	2097/2209	0.976	(0.755–1.262)	0.853	77.2	<0.001	−1.04	0.317
bb + Bb vs. BB	15	2097/2209	1.233	(0.851–1.787)	0.269	70.3	<0.001	0.18	0.864
bb vs. Bb + BB	15	2097/2209	0.902	(0.613–1.326)	0.599	70.8	<0.001	0.76	0.463
bb vs. BB	15	2097/2209	1.364	(0.838–2.221)	0.212	59.3	0.002	0.39	0.704
TaqI t vs. T	15	2028/2047	1.005	(0.801–1.260)	0.968	62.3	0.001	−0.27	0.789
tt + Tt vs. TT	15	2028/2047	1.029	(0.821–1.299)	0.803	53.3	0.008	0.32	0.758
tt vs. Tt + TT	15	2028/2047	0.986	(0.742–1.310)	0.922	28.8	0.140	−0.13	0.897
tt vs. TT	15	2028/2047	1.085	(0.616–1.910)	0.778	50.4	0.013	0.04	0.970
ApaI a vs. A	8	1276/1506	0.913	(0.818–1.019)	0.106	23.0	0.246	NA	NA
aa + Aa vs. AA	8	1276/1506	0.891	(0.753–1.054)	0.178	30.1	0.187	NA	NA
aa vs. Aa + AA	8	1276/1506	0.885	(0.733–1.069)	0.206	00.0	0.705	NA	NA
aa vs. AA	8	1276/1506	0.836	(0.666–1.051)	0.125	13.1	0.328	NA	NA

The bold values indicate that the OR (95%CI) does not include 1, and the p-value is <0.05.