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. 2024 Aug 20;11:1455673. doi: 10.3389/fmed.2024.1455673

Table 2.

ANA fine specificities (ALBIA) in relation to mean age and sex among the 825 healthy blood donors.

ANA fine specificity Positive, n (%) Mean age (years) Positive, n (%) Females, n (%) Males, n (%) p value
dsDNA 7 (0.8) 36.9 7 (0.8) 5 (71.4) 2 (28.6) 0.23
Ro60/SSA 16 (1.9) 48.9 16 (1.9) 5 (31.3) 11 (68.8) 0.15
Ro52/SSA 5 (0.6) 48.4 5 (0.6) 3 (60) 2 (40) 0.25
La/SSB 4 (0.5) 53.0 4 (0.5) 1 (25) 3 (75) 0.34
Sm 0 0 0 0
SmRNP 1 (0.1) 25.0 1 (0.1) 0 1 (100)
U1-RNP 15 (1.8) 43.6 15 (1.8) 12 (80) 3 (20) 0.014
Scl70 3 (0.4) 52.0 3 (0.4) 0 3 (100)
Jo1 5 (0.6) 43.6 5 (0.6) 2 (40) 3 (60) 0.69
CENP-B 2 (0.2) 49.5 2 (0.2) 0 2 (100)
RiboP 2 (0.2) 28.5 2 (0.2) 1 (50) 1 (50) 0.97
Histone 2 (0.2) 46.0 2 (0.2) 1 (50) 1 (50) 0.97
PmScl 18 (2.2) 50.6 18 (2.2) 6 (33.3) 12 (66.7) 0.18
PCNA 13 (1.6) 35.7 13 (1.6) 4 (30.8) 9 (69.2) 0.19
≥ 1 specificity 82 (9.9) 45.1 82 (9.9) 34 (41.5) 48 (58.5) 0.16
> 1 specificity 5 (0.6) 45.8 5 (0.6) 2 (40) 3 (60) 0.69
Negative 743 (90.1) 42.3 743 (90.1) 369 (91.6) 374 (88.6) 0.16

Bold value indicates that statistical significance was reached; i.e., U1-RNP positivity was more common among female HBD.