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. 2024 Aug 20;15:1440932. doi: 10.3389/fneur.2024.1440932

Table 1.

Comparison of motor and non-motor symptoms in MSA patients with and without SRBD.

Characteristics All MSA patients (n = 66) With SRBD (n = 52) Without SRBD (n = 14) p
Male/Female 40/26 31/21 9/5 0.753
Age(years) 63.05 ± 10.13 63.69 ± 9.60 60.64 ± 11.58 0.325
Disease onset (year) 60.15 ± 10.3 60.74 ± 9.91 57.93 ± 11.01 0.370
Disease duration (year) 2.79 ± 2.78 2.61 ± 1.86 2.84 ± 2.98 0.962
UMSARS I 13.23 ± 5.8 13.06 ± 5.74 13.86 ± 5.99 0.648
UMSARS II 16.52 (12–20.25) 16.33 ± 6.12 17.29 ± 6.23 0.638
UMSARS IV 1.74 ± 0.99 1.65 ± 0.84 2.00 ± 1.36 0.751
NMSS 49.35 ± 26.4 49.79 ± 26.23 47.71 ± 28.16 0.797
HAMA 11.14 ± 7.88 10.84 ± 7.29 12.21 ± 9.64 0.804
HAMD 10.28 ± 6.99 9.78 ± 6.14 12.07 ± 9.23 0.642
ESS 7.11 (2.75–11.00) 7.23 (2.25–11.75) 6.64 (2.75–9.00) 0.571
FSS 21.71 (11–30) 22.98 (11–34) 17 (12.50–21.25) 0.723
MMSE 24.58 (22–29) 24.13 (21.25–28) 26.21 (24.50–29.00) 0.172
PLMS (%) 47 (71.2) 35 (67.3) 12 (85.7) 0.318
PSQI 6.64 (3.0–9.5) 6.90 (3–9) 5.64 (1.75–10.00) 0.194

ESS, Epworth Sleepiness Scales; FSS, Fatigue severity scale; HAMA, Hamilton anxiety scale; HAMD, Hamilton depression scale; MSA, Multiple system atrophy; MMSE, Mini-mental state examination; NMSS, Non-motor symptoms scale; PLMS, Periodic limb movements syndrome; PSQI, Pittsburgh sleep quality index; SRBD, Sleep related breathing disordered; and UMSARS, Unified multiple-system atrophy rating scale.

Values are n (%), mean ± SD or median (interquartile range).