Table 1.
Comparison of motor and non-motor symptoms in MSA patients with and without SRBD.
| Characteristics | All MSA patients (n = 66) | With SRBD (n = 52) | Without SRBD (n = 14) | p |
|---|---|---|---|---|
| Male/Female | 40/26 | 31/21 | 9/5 | 0.753 |
| Age(years) | 63.05 ± 10.13 | 63.69 ± 9.60 | 60.64 ± 11.58 | 0.325 |
| Disease onset (year) | 60.15 ± 10.3 | 60.74 ± 9.91 | 57.93 ± 11.01 | 0.370 |
| Disease duration (year) | 2.79 ± 2.78 | 2.61 ± 1.86 | 2.84 ± 2.98 | 0.962 |
| UMSARS I | 13.23 ± 5.8 | 13.06 ± 5.74 | 13.86 ± 5.99 | 0.648 |
| UMSARS II | 16.52 (12–20.25) | 16.33 ± 6.12 | 17.29 ± 6.23 | 0.638 |
| UMSARS IV | 1.74 ± 0.99 | 1.65 ± 0.84 | 2.00 ± 1.36 | 0.751 |
| NMSS | 49.35 ± 26.4 | 49.79 ± 26.23 | 47.71 ± 28.16 | 0.797 |
| HAMA | 11.14 ± 7.88 | 10.84 ± 7.29 | 12.21 ± 9.64 | 0.804 |
| HAMD | 10.28 ± 6.99 | 9.78 ± 6.14 | 12.07 ± 9.23 | 0.642 |
| ESS | 7.11 (2.75–11.00) | 7.23 (2.25–11.75) | 6.64 (2.75–9.00) | 0.571 |
| FSS | 21.71 (11–30) | 22.98 (11–34) | 17 (12.50–21.25) | 0.723 |
| MMSE | 24.58 (22–29) | 24.13 (21.25–28) | 26.21 (24.50–29.00) | 0.172 |
| PLMS (%) | 47 (71.2) | 35 (67.3) | 12 (85.7) | 0.318 |
| PSQI | 6.64 (3.0–9.5) | 6.90 (3–9) | 5.64 (1.75–10.00) | 0.194 |
ESS, Epworth Sleepiness Scales; FSS, Fatigue severity scale; HAMA, Hamilton anxiety scale; HAMD, Hamilton depression scale; MSA, Multiple system atrophy; MMSE, Mini-mental state examination; NMSS, Non-motor symptoms scale; PLMS, Periodic limb movements syndrome; PSQI, Pittsburgh sleep quality index; SRBD, Sleep related breathing disordered; and UMSARS, Unified multiple-system atrophy rating scale.
Values are n (%), mean ± SD or median (interquartile range).