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. 2024 Aug 20;14:1393990. doi: 10.3389/fonc.2024.1393990

Table 1.

Distribution of demographic and clinical information.

Variables Total population
(N = 1,298; 100.0%)
Training cohort
(N = 910; 70.1%)
Validation cohort
(N = 388; 29.9%)
P
N % N % N %
Lung metastasis 0.945
No 1,172 90.3 822 90.3 350 90.2
Yes 126 9.7 88 9.7 38 9.8
Age (years) 0.432
<18 197 15.2 136 14.9 61 15.7
18–50 476 36.7 344 37.8 132 34.0
>50 625 48.2 430 47.3 195 50.3
Race 0.115
White 1,110 85.5 789 86.7 321 82.7
Black 90 6.9 55 6.0 35 9.0
Other 98 7.6 66 7.3 32 8.2
Sex 0.086
Male 779 60.0 560 61.5 219 56.4
Female 519 40.0 350 38.5 169 43.6
Year of birth 0.965
<1970 779 60.0 548 60.2 231 59.5
1970–2000 474 36.5 331 36.4 143 36.9
>2000 45 3.5 31 3.4 14 3.6
ICD O 3 histologic type 0.233
Osteosarcoma 239 18.4 161 17.7 78 20.1
Chondrosarcoma 433 33.4 301 33.1 132 34.0
Ewing’s sarcoma 280 21.6 191 21.0 89 22.9
Chordoma 346 26.7 257 28.2 89 22.9
Grade 0.338
Grade I 147 11.3 98 10.8 49 12.6
Grade II 188 14.5 131 14.4 57 14.7
Grade III 138 10.6 90 9.9 48 12.4
Grade IV 197 15.2 135 14.8 62 16.0
Unknown 628 48.4 456 50.1 172 44.3
Lymph node involvement 0.245
No 1,198 92.3 845 92.9 353 91.0
Yes 100 7.7 65 7.1 35 9.0
Other site metastasis 0.830
No 1,147 88.4 803 88.2 344 88.7
Yes 151 11.6 107 11.8 44 11.3
Tumor size (cm) 0.151
<5 267 20.6 189 20.8 78 20.1
5–10 545 42.0 367 40.3 178 45.9
>10 486 37.4 354 38.9 132 34.0
Tumor extension 0.402
Inside periosteum 457 35.2 327 35.9 130 33.5
Beyond periosteum 841 64.8 583 64.1 258 66.5
Origin laterality 0.471
Left 292 22.5 204 22.4 88 22.7
Right 321 24.7 217 23.8 104 26.8
Other 685 52.8 489 53.7 196 50.5
Reporting source 0.688
Hospital 1,275 98.2 893 98.1 382 98.5
Other 23 1.8 17 1.9 6 1.5
Insurance 0.961
Insured 843 64.9 591 64.9 252 64.9
Medicaid 165 12.7 117 12.9 48 12.4
Other 290 22.3 202 22.2 88 22.7
Marriage 0.839
Married 585 45.1 417 45.8 168 43.3
Divorced 67 5.2 49 5.4 18 4.6
Single 534 41.1 366 40.2 168 43.3
Widowed 62 4.8 44 4.8 18 4.6
Other 50 3.9 34 3.7 16 4.1

Chi-square test: these values are statistically significant at a p-value <0.05.