Table 3.
Multivariate Cox regression for analyzing the prognosis-associated factors in the metastasis subgroup (n = 122).
| Variables | Multivariate analysis | |
|---|---|---|
| Hazard ratio (95% CI) | p-Value | |
| Age (years) | ||
| <18 | 1 (reference) | |
| 18–50 | 1.438 (0.757–2.732) | 0.267 |
| >50 | 2.705 (1.237–5.916) | 0.013* |
| ICD O 3 histologic type | ||
| Osteosarcoma | 1 (reference) | |
| Chondrosarcoma | 0.965 (0.476–1.955) | 0.000* |
| Ewing’s sarcoma | 0.259 (0.135–0.494) | 0.007* |
| Chordoma | 0.100 (0.019–0.536) | 0.922 |
| Other site metastasis | ||
| No | 1 (reference) | |
| Yes | 1.464 (0.918–2.335) | 0.109 |
| Grade | ||
| Grade I | 1 (reference) | |
| Grade II | 0.869 (0.103–7.333) | 0.897 |
| Grade III | 0.267 (0.072–0.988) | 0.048* |
| Grade IV | 0.923 (0.460–1.851) | 0.821 |
| Unknown | 1.165 (0.680–1.995) | 0.579 |
| Surg prim site | ||
| No | 1 (reference) | |
| Yes | 0.544 (0.301–0.984) | 0.044* |
| Lymph nodes removed | ||
| No | 1 (reference) | |
| Yes | 0.900 (0.309–2.622) | 0.846 |
| Chemotherapy | ||
| No/unknown | 1 (reference) | |
| Yes | 0.702 (0.363–1.358) | 0.293 |
Multivariable Cox regression: (*) at a p-value <0.05.
Grade I, well differentiated; Grade II, moderately differentiated; Grade III, poorly differentiated; Grade IV, undifferentiated.