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. 2024 Aug 20;15:1452849. doi: 10.3389/fimmu.2024.1452849

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Copyright © 2024 Fu, Wang and Cai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A leave-one-out analysis of statistically significant differences in the causal effects of IL-6R inhibitors on seven types of diseases, including: (A) COVID-19, (B) Rheumatoid arthritis, (C) Idiopathic pulmonary fibrosis, (D) Parkinson’s disease, (E) Type 2 diabetes, (F) Asthma, (G) Asthmatic pneumonia.The Y-axis corresponds to each excluded rsid number and the ‘all’ condition not excluded by the IVW method. The X-axis corresponds to specific IVW values, with black and red dots representing beta effect values, and the lines indicating the confidence intervals of these beta values.