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. 2024 Sep 2;2:63. doi: 10.1038/s44276-024-00077-3

Table 2.

Associations between dietary calcium intake, supplemental calcium intake and total calcium intake in relation to CRC-specific and all-cause mortality in CRC survivors.

Dietary calcium intake
All-cause mortality
Sex- and cohort- specific quartiles Quartile 1 Quartile 2 Quartile 3 Quartile 4 P for trend
Number/events 3368/1216 3387/1188 3157/1124 3173/1125
HR (95%CI) 1.0 (ref) 0.97 (0.89–1.05) 0.99 (0.91–1.07) 1.00 (0.92–1.09) 0.862
CRC-specific mortality
Number/events 3298/745 3345/745 3106/689 3129/709 0.824
HR (95%CI) 1.00 (Ref) 0.98 (0.88–1.08) 1.00 (0.90–1.10) 1.01 (0.91–1.12)
Supplemental calcium intake
All-cause mortality
Supplement use <1 pill ≥1 pill
Number/events 9755/3708 2082/766
HR (95%CI) 1.00 (Ref) 0.97 (0.89–1.06)
CRC-specific mortality
Supplement use <1 pill ≥1 pill
Number/events 9399/2111 2077/476
HR (95%CI) 1.00 (Ref) 1.01 (0.90–1.13)
Total calcium intake (dietary and supplemental intake)
All-cause mortality
Sex- and cohort- specific quartiles Quartile 1 Quartile 2 Quartile 3 Quartile 4 P for trend
Number/events 1501/602 1487/573 1436/535 1546/616
HR (95%CI) 1 (Ref) 0.98 (0.88–1.10) 0.95 (0.85–1.07) 0.99 (0.88–1.11) 0.735
CRC-specific mortality
Number/events 1450/338 1440/313 1388/287 1496/434
HR (95%CI) 1.0 (ref) 0.93 (0.80–1.08) 0.88 (0.75–1.03) 0.99 (0.85–1.15) 0.707