Table 2.
Associations between dietary calcium intake, supplemental calcium intake and total calcium intake in relation to CRC-specific and all-cause mortality in CRC survivors.
| Dietary calcium intake | |||||
|---|---|---|---|---|---|
| All-cause mortality | |||||
| Sex- and cohort- specific quartiles | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P for trend |
| Number/events | 3368/1216 | 3387/1188 | 3157/1124 | 3173/1125 | |
| HR (95%CI) | 1.0 (ref) | 0.97 (0.89–1.05) | 0.99 (0.91–1.07) | 1.00 (0.92–1.09) | 0.862 |
| CRC-specific mortality | |||||
| Number/events | 3298/745 | 3345/745 | 3106/689 | 3129/709 | 0.824 |
| HR (95%CI) | 1.00 (Ref) | 0.98 (0.88–1.08) | 1.00 (0.90–1.10) | 1.01 (0.91–1.12) | |
| Supplemental calcium intake | |||||
| All-cause mortality | |||||
| Supplement use | <1 pill | ≥1 pill | |||
| Number/events | 9755/3708 | 2082/766 | |||
| HR (95%CI) | 1.00 (Ref) | 0.97 (0.89–1.06) | |||
| CRC-specific mortality | |||||
| Supplement use | <1 pill | ≥1 pill | |||
| Number/events | 9399/2111 | 2077/476 | |||
| HR (95%CI) | 1.00 (Ref) | 1.01 (0.90–1.13) | |||
| Total calcium intake (dietary and supplemental intake) | |||||
| All-cause mortality | |||||
| Sex- and cohort- specific quartiles | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P for trend |
| Number/events | 1501/602 | 1487/573 | 1436/535 | 1546/616 | |
| HR (95%CI) | 1 (Ref) | 0.98 (0.88–1.10) | 0.95 (0.85–1.07) | 0.99 (0.88–1.11) | 0.735 |
| CRC-specific mortality | |||||
| Number/events | 1450/338 | 1440/313 | 1388/287 | 1496/434 | |
| HR (95%CI) | 1.0 (ref) | 0.93 (0.80–1.08) | 0.88 (0.75–1.03) | 0.99 (0.85–1.15) | 0.707 |