Table 1.
Demographic and clinical characteristics of study population at baseline. Data are presented as mean ± SD or n (%). BMI = body mass index
| Variables | Total (N = 32) |
No treatment (N = 15) |
Exenatide (N = 17) | p-value |
|---|---|---|---|---|
| Age (years) | 73 ± 5 | 72 ± 6 | 74 ± 4 | 0.40 |
| Male sex n (%) | 16(50) | 8(53) | 8(47) | 0.87 |
| Smoking habit n (%) | 3(9) | 3(21) | 0(0) | 0.17 |
| Alcohol consumption n (%) | 23(72) | 10(64) | 13(76) | 0.46 |
| Weight (Kg) | 73.0 ± 11.1 | 75.8 ± 11.4 | 70.5 ± 10.5 | 0.18 |
| BMI (Kg/m2) | 27.2 ± 3.4 | 27.6 ± 3.3 | 27.0 ± 3.6 | 0.65 |
| BMI > 30 kg/m2 | 6(18.8) | 4(27) | 2(12) | 0.28 |
| Waist circumference (cm) | 97.0 ± 9.0 | 98.5 ± 11.5 | 96.1 ± 6.9 | 0.46 |
| Systolic blood pressure (mmHg) | 132 ± 17 | 132 ± 14 | 133 ± 19 | 0.88 |
| Diastolic blood pressure (mmHg) | 79 ± 11 | 80 ± 11 | 79 ± 11 | 0.76 |
| Heart rate (bpm) | 69 ± 8 | 71 ± 7 | 67 ± 8 | 0.24 |
| Fasting plasma glucose (mg/dl) | 92 ± 8 | 92 ± 11 | 92 ± 7 | 0.80 |
| HbA1c (mmol/mol) | 36 ± 4 | 37 ± 3 | 35 ± 4 | 0.33 |
| Dysglycemia | 11(34) | 6(40) | 5(29) | 0.53 |
| AST (U/L) | 26 ± 8 | 29 ± 10 | 24 ± 5 | 0.07 |
| ALT (U/L) | 23 ± 13 | 25 ± 16 | 21 ± 10 | 0.68 |
| Lipase (U/L) | 20 ± 13 | 19 ± 11 | 20 ± 15 | 0.74 |
| Creatinine (mg/dL) | 0.81 ± 0.17 | 0.85 ± 0.16 | 0.77 ± 0.18 | 0.28 |
| eGFR (mL/min/1.73 m2) | 82 ± 11 | 81 ± 12 | 83 ± 11 | 0.49 |