Table 4.

Multivariate analysis results for PCH

Variables	Univariate analyses			Multivariate analyses (enter)			Multivariate analyses (backward: LR)
	OR	95%CI	p-value	OR	95%CI	p-value	OR	95%CI	p-value
Initial NBS-TSH level	1.031	1.020–1.043	< 0.001	1.021	1.002–1.040	0.029	1.019	1.003–1.034	0.019
Initial serum TSH level	1.009	1.002–1.017	0.017	0.966	0.984–1.009	0.569	–	–	–
LT4 dose at withdrawal	7.243	3.822–13.726	< 0.001	10.269	4.464–23.622	< 0.001	6.511	3.16–13.41	< 0.001

Enter: Nagelkerke R2: 0.476; Hosmer–Lemeshow test p value: 0.108; predicted percentage: 78.8%. Backward: LR: nagelkerke R2: 0.416; Hosmer–Lemeshow test p value: 0.316; predicted percentage: 78.8%

PCH Permanent congenital hypothyroidism, NBS Newborn screening, TSH Thyroid stimulating hormone, LT4 L-thyroxine

Initial NBS-TSH level and LT4 dose at the withdrawal were determined as predictors of PCH