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Diabetic model of islet damage in rodents.
| Induction mechanism | Model | Induction mechanism | Model |
|---|---|---|---|
| Chemical induction | Streptozocin (single injection 150–200 mg/kg or injections 50 mg/kg for 5 days) | Genetic induction | Akita mouse |
| Alloxan (single injection 100–200 mg/kg) | Spontaneous autoimmunity | NOD mouse | |
| Virus induction | Coxsackie B virus | BB mouse | |
| Cerebral myocarditis virus | LEW.1NR1/ztm‐iddm rat | ||
| Kilham rat virus | Lewis‐IDDM rat | ||
| LCMV insulin promoter | KDP rat |
