Table 1.
Age at starting TG, y | 42 (26-57) |
Sex | |
Female | 70 (61) |
Male | 44 (39) |
Disease duration, y | 3 (1-8) |
Inflammatory bowel disease subtype | |
Ulcerative colitis | 51 (45) |
Crohn’s disease | 60 (53) |
IBD undetermined | 3 (3) |
Montreal Classification (UC) | |
E1: proctitis | 3 (6) |
E2: left-sided colitis | 26 (51) |
E3: extensive colitis | 22 (43) |
Montreal Classification (CD) | |
Age at diagnosis | |
A1 (≤16 y) | 1 (2) |
A2 (17-40 y) | 35 (58) |
A3 (≥40 y) | 23 (38) |
Missing | 1 (2) |
Disease location | |
L1: only terminal ileum | 21 (35) |
L2: only colon | 20 (33) |
L3: ileum and colon | 18 (30) |
+L4: locations proximal of ileum | 1 (2) |
+P: perianal disease | 6 (10) |
Missing | 1 (2) |
Behavior | |
B1: nonstricturing, nonpenetrating | 49 (82) |
B2: stricturing | 8 (13) |
B3: penetrating | 2 (3) |
Missing | 1 (2) |
Previous bowel surgery | 6 (5) |
Smoking status | |
Current | 16 (14) |
Former | 22 (19) |
Never | 62 (54) |
Missing | 14 (12) |
Comedication at the start of TG | |
Corticosteroids | 43 (38) |
Corticosteroid enema | 10 (9) |
Mesalazine enema | 4 (4) |
Mesalazine suppository | 2 (2) |
Mesalazine | 48 (42) |
Budesonide | 33 (29) |
Combination enema (mesalazine + corticosteroids) | 9 (8) |
None | 11 (10) |
Values are median (interquartile range) or n (%).
Abbreviations: CD, Crohn’s disease; TG, thioguanine; UC, ulcerative colitis.