. 2024 Feb 27;30(9):1556–1565. doi: 10.1093/ibd/izae027

Table 2.

Bivariate cross-twin cross-trait correlations and AE bivariate quantitative genetic model estimates for IBD and allergic diseases in all 5 twin subcohorts combined.

	Phenotypic correlations	Cross-twin cross-trait correlations (95%CI)		Twin model estimates (95% CI)^a
	Phenotypic correlations	r_MZ	r_DZ	r_a	r_e
IBD and asthma	0.05 (0.01 to 0.09)	0.06 (−0.02 to 0.14)	−0.06 (−0.12 to 0.00)	0.05 (−0.03 to 0.12)	0.08 (−0.10 to 0.27)
IBD and allergic rhinitis	0.07 (0.03 to 0.11)	0.04 (−0.03 to 0.11)	0.02 (−0.03 to 0.06)	0.06 (−0.03 to 0.15)	0.12 (−0.04 to 0.29)
IBD and eczema	0.11 (0.07 to 0.15)	0.09 (0.01 to 0.17)	−0.03 (−0.09 to 0.02)	0.06 (−0.05 to 0.17)	0.16 (0.00 to 0.32)

Abbreviations: a, additive genetic component; CI, confidence interval; e, nonshared environmental component (including measurement errors); IBD, inflammatory bowel disease.

^aAll models were adjusted for sex and birth year (continuous, standardized).