Table 2.
Variable | Asianb | Native Hawaiian/Pacific Islander b | Hispanic | White, non-Hispanic | ||||
---|---|---|---|---|---|---|---|---|
Cases, no. (%) | Controls, no. (%) | Cases, no. (%) | Controls, no. (%) | Cases, no. (%) | Controls, no. (%) | Cases, no. (%) | Controls, no. (%) | |
BMI, age 18 y | ||||||||
<18.5 | 133 (23.2) | 141 (19.4) | 10 (10.3) | 9 (5.4) | 56 (13.2) | 73 (13.6) | 1110 (16.6) | 1634 (18.0) |
18.5-24.9 | 402 (70.0) | 540 (74.4) | 60 (61.9) | 106 (64.6) | 303 (71.5) | 394 (73.6) | 4938 (73.6) | 6754 (74.3) |
25.0-29.9 | 30 (5.2) | 40 (5.5) | 15 (15.5) | 31 (18.9) | 49 (11.6) | 52 (9.7) | 512 (7.6) | 547 (6.0) |
≥30.0 | 9 (1.6) | 5 (0.7) | 12 (12.4) | 18 (11.0) | 16 (3.8) | 16 (3.0) | 148 (2.2) | 161 (1.8) |
Missing data | 211 | 223 | 2 | 3 | 81 | 109 | 3273 | 5112 |
Smoking | ||||||||
Never | 636 (83.1) | 688 (74.2) | 58 (58.6) | 86 (51.5) | 248 (62.3) | 323 (63.7) | 4959 (53.3) | 7168 (53.1) |
Former | 32 (4.2) | 87 (9.4) | 14 (14.1) | 41 (24.6) | 107 (26.9) | 132 (26.0) | 3192 (34.3) | 4858 (36.0) |
Current | 97 (12.7) | 152 (16.4) | 27 (27.3) | 40 (24.0) | 43 (10.8) | 52 (10.3) | 1162 (12.5) | 1464 (10.9) |
Missing data | 20 | 22 | 0 | 0 | 107 | 137 | 668 | 718 |
Family history of breast cancer | ||||||||
No | 466 (87.1) | 476 (84.3) | 39 (69.6) | 34 (59.7) | 324 (83.9) | 425 (89.9) | 6649 (79.8) | 10259 (83.2) |
Yes | 69 (12.9) | 89 (15.8) | 17 (30.4) | 23 (40.4) | 62 (12.1) | 48 (10.2) | 1679 (20.2) | 2073 (16.8) |
Missing data | 250 | 384 | 43 | 110 | 119 | 171 | 1653 | 1876 |
Family history of ovarian cancer | ||||||||
No | 489 (95.7) | 511 (96.2) | 47 (94.0) | 40 (97.6) | 346 (91.8) | 436 (94.4) | 7656 (93.5) | 11792 (97.0) |
Yes | 22 (4.3) | 20 (3.8) | 3 (6.0) | 1 (1.1) | 31 (8.2) | 26 (5.6) | 530 (6.5) | 366 (3.0) |
Missing data | 274 | 418 | 49 | 126 | 128 | 182 | 1795 | 2050 |
Histology/grade | ||||||||
High-grade serous | 352 (44.8) | 46 (46.5) | 323 (64.0) | 6512 (65.2) | ||||
Low-grade serous | 5 (0.6) | 0 | 26 (5.1) | 310 (3.1) | ||||
Endometrioid | 98 (12.5) | 13 (13.1) | 48 (9.5) | 999 (10.0) | ||||
Mucinous | 85 (10.8) | 13 (13.1) | 42 (8.3) | 482 (4.8) | ||||
Clear cell | 148 (18.9) | 15 (15.2) | 24 (4.8) | 675 (6.8) | ||||
Mixed cell | 16 (2.0) | 1 (1.0) | 4 (0.8) | 293 (2.9) | ||||
Other epithelial | 81 (10.4) | 11 (11.1) | 38 (7.5) | 710 (7.1) | ||||
Stage | ||||||||
Localized | 221 (28.2) | 34 (34.3) | 98 (19.1) | 1416 (14.2) | ||||
Regional | 146 (18.6) | 20 (20.2) | 75 (14.6) | 1397 (14.0) | ||||
Distant | 312 (39.8) | 43 (43.4) | 314 (61.2) | 5912 (59.3) | ||||
Unknown stage | 106 (13.5) | 2 (2.0) | 18 (3.6) | 1256 (12.6) |
Abbreviations: BMI, body mass index; DOV, Diseases of the Ovary and their Evaluation Study; HAW, Hawaii Ovarian Cancer Case-Control Study; MAY, Mayo Clinic Ovarian Cancer Case-Control Study; NJO, the New Jersey Ovarian Cancer Study; OC, oral contraceptive; OVA, Ovarian Cancer in Alberta and British Columbia Study; STA, Genetic Epidemiology of Ovarian Cancer; USC, Los Angeles County Case-Control Studies of Ovarian Cancer.
a The following variables were missing for certain study sites: breastfeeding (MAY); endometriosis (OVA, STA); BMI recent (OVA, STA); BMI at age 18 (MAY, OVA, STA); postmenopausal hormone use (STA). One study (MAY) was an outlier and was excluded from hysterectomy analysis.
b Asian includes Chinese, Japanese, Korean, Filipino, Vietnamese, Thai. Native Hawaiian/Pacific Islander includes Hawaiian, Pacific Islander (Tongan, Samoan, Māori, Palauan, Chuukese, Micronesian).
c Reference date is defined as age at diagnosis for cases and age at interview for control participants.
d Breastfeeding refers to parous women only.
ePostmenopausal hormone use refers to use of estrogen only, estrogen plus progesterone, and unknown formulation types among postmenopausal women only.
f Recent BMI refers to 1 year before the reference date for all sites, except for DOV and HAW (5 years before the reference date). BMI calculated as weight (kg) divided by height (m2).