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. 2024 Aug 12;7(4):463–471. doi: 10.1002/agm2.12350

TABLE 2.

Angiographic, procedural characteristics and 24‐month outcomes for the patients.

Total population 1:3 Propensity‐matched patients
Prior‐failed‐attempt Initial‐attempt P value Initial‐attempt P value
(n = 49) (n = 435) (n = 147)
Angiographic characteristics
Multi‐vessel disease 43 (87.8) 388 (89.2) 0.948 126 (85.7) 0.905
LM disease 5 (10.2) 24 (5.5) 0.199 5 (3.4) 0.125
Target CTO vessel 0.123 0.634
LAD 25 (51) 173 (39.8) 75 (51)
LCX 4 (8.2) 82 (18.9) 7 (4.8)
RCA 20 (40.8) 180 (41.4) 65 (44.2)
Syntax score 19.5 (16.5, 24.5) 23.25 (17.0, 30.5) 0.028 22.5 (16.0, 28.5) 0.235
J‐CTO score ≥2 31 (77.5) 175 (41.1) <0.001 57 (38.8) <0.001
Rentrop grade 3 21 (52.5) 200 (46.9) 0.612 80 (54.4) 0.62
ISR CTO 9 (18.4) 75 (17.2) 1.000 28 (19) 1.000
Procedural characteristics
Femoral artery access 21 (49.0) 90 (20.5) <0.001 41 (27.9) 0.009
Dual injection 28 (57.1) 207 (47.6) 0.204 62 (42.2) 0.069
Retrograde approach 16 (32.7) 76 (17.5) 0.010 5 (3.4) <0.001
IVUS procedure 11 (22.4) 64 (14.8) 0.235 28 (19) 0.757
Contrast volume (mL) 319.5 ± 121.8 244.1 ± 74.0 0.192 258.6 ± 69.4 0.284
Fluoroscopy time (min) 66.8 ± 33.4 41.1 ± 26.4 0.067 46.7 ± 28.7 0.218
Type of intervention 0.549 0.083
Stent implantation 22 (84.6) 309 (90.4) 117 (95.9)
Balloon PTCA 4 (15.4) 33 (9.6) 5 (4.1)
Successful CTO revascularization 26 (53.1) 342 (78.6) <0.001 122 (83.3) <0.001
Non‐CTO lesion PCI 9 (18.8) 167 (38.7) 0.01 55 (37.4) 0.044
CR 13 (26.5) 203 (46.7) 0.011 76 (51.7) 0.004
Major procedural complications 1 (2.0) 10 (2.3) 1.000 1 (0.7) 0.438
Acute stent thrombosis 0 (0) 3 (0.7) 1.000 1 (0.7) 1.000
Cardiac death 0 (0) 4 (0.9) 1.000 0 (0)
TVR 2 (4.1) 48 (11.0) 0.130 12 (8.2) 0.522
MACE 2 (4.1) 56 (12.9) 0.072 13 (8.8) 0.438
MACE in successful CTO revascularization population 1/26 (3.8) 40/342 (11.7) 0.366 10/122 (8.2) 0.722

Note: Values are mean ± SD, n (%), n/N (%), or median (interquartile range).

Abbreviations: CR, complete revascularization; CTO, chronic total occlusion; ISR, in‐stent restenosis; J‐CTO, Japanese‐CTO; IVUS, intravascular ultrasound; LAD, left anterior descending artery; LCX, left circumflex; LM, left main; MACE, major adverse cardiac event; PCI, percutaneous coronary intervention;RCA, right coronary artery; TVR, target vessel revascularization.