Table 3.
Comparison of parameters during the test in 3 types
| Overproduction type 1 n = 69 |
Underexcretion type 2 n = 428 |
Combined type 3 n = 129 |
p-value† | |||
|---|---|---|---|---|---|---|
| 1 vs 2 | 1 vs 3 | 2 vs 3 | ||||
| ΔsUA (μmol/L) | ||||||
| Unadjusted | − 88.81 ± 63.01 | − 57.32 ± 61.19 | − 65.22 ± 44.13 | < 0.001 | 0.021 | NS |
| Adjusted for age | − 89.94 ± 7.06 | − 57.29 ± 2.82 | − 64.71 ± 5.14 | < 0.001 | 0.012 | NS |
| Adjusted for BMI | − 88.59 ± 7.01 | − 57.69 ± 2.83 | − 64.07 ± 5.19 | < 0.001 | 0.015 | NS |
| Adjusted for sUA | − 92.27 ± 6.49 | − 59.13 ± 2.61 | − 57.34 ± 4.80 | < 0.001 | < 0.001 | NS |
| Adjusted for eGFR | − 87.73 ± 7.06 | − 57.24 ± 2.82 | − 66.05 ± 5.16 | < 0.001 | 0.042 | NS |
| ΔSBP (mmHg) | − 4.58 ± 14.38 | − 4.38 ± 13.14 | − 1.26 ± 14.02 | NS | ||
| ΔDBP (mmHg) | − 2.48 ± 10.58 | − 2.61 ± 8.83 | − 0.98 ± 10.60 | NS | ||
| ΔBMI (kg/m2) | 0.00 (− 0.34, 0.00) | 0.00 (− 0.34, 0.00) | 0.00 (− 0.34, 0.00) | NS | ||
| ΔALT (U/L) | 0.00 (− 6.00, 9.00) | − 1.00 (− 8.00, 3.00) | − 4.00 (− 11.00, 3.00) | NS | ||
| ΔAST (U/L) | 0.00 (− 4.00, 3.00) | − 1.00 (− 4.00, 2.00) | − 1.00 (− 4.50, 1.00) | NS | ||
| ΔFPG (mmol/L) | 0.35 ± 1.38 | − 0.10 ± 0.72 | − 0.02 ± 0.68 | < 0.001 | 0.007 | NS |
| ΔTG (mmol/L) | − 0.31 (− 0.81, 0.13) | − 0.07 (− 0.53, 0.34) | − 0.25 (− 0.83, 0.12) | 0.008 | NS | 0.004 |
| ΔTC (mmol/L) | − 0.17 ± 0.72 | − 0.05 ± 0.58 | − 0.09 ± 0.57 | NS | ||
| ΔBUN (mmol/L) | − 0.32 ± 1.13 | − 0.63 ± 1.17 | − 0.51 ± 1.11 | NS | ||
| ΔScr (μmol/L) | 0.11 ± 15.82 | − 0.70 ± 12.58 | 1.25 ± 13.07 | NS | ||
| ΔeGFR [mL min−1 (1.73 m2)−1] | 0.72 ± 14.44 | 0.43 ± 10.33 | 1.85 ± 9.72 | NS | ||
Data are expressed as the mean ± SD, median (quartile)
NS no significance, p > 0.05
†p-values are from one-way ANOVA and Kruskal–Wallis ANOVA, accompanying correspond to post hoc multiple comparison test (Bonferroni adj.) performed if significant ANOVA p-values