Table 4.

Comparison of the level of inflammation between different study groups

Group	Grade 0 N (%)	Grade 1 N (%)	Grade 2 N (%)	Grade 3 N (%)	Grade 4 N (%)
A	10 (88.3)	2 (16.7)	0 (0.0)	0 (0.0)	0 (0.0)
B	4 (33.3)	7 (58.3	1 (8.3)	0 (0.0)	0 (0.0)
C	7 (58.3)	5 (41.7)	0 (0.0)	0 (0.0)	0 (0.0)
D	8 (66.7)	2 (16.7)	0 (0.0)	2 (16.7)	0 (0.0)
E	4 (33.3)	1 (8.3)	3 (25.0)	2 (16.7)	2 (16.7)
F	8 (66.7)	1 (8.3)	3 (25.0)	0 (0.0)	0 (0.0)

Grade 0: No acute inflammation – Grade 1: Perivascular scattered acute inflammatory cells – Grade 2: Perivascular and submucosal scattered acute inflammatory cells – Grade 3: Submucosal band-like inflammatory infiltrate, less than 1/4 of one lower field – Grade 4: Submucosal band-like inflammatory infiltrate, between 1/4 and 1/2 of one lower area without tissue necrosis, PMSE: Plantago major standardized extract-Group A: 5% PMSE nano emulsion-Group B:10% PMSE nano emulsion-Group C: 20% PMSE nano emulsion-Group D: nano emulsion without any PMSE -Group E: 5%PMSE - Group F: control