Figure 6. Components of Wnt/PCP signaling are conserved across mouse and human adrenals.

UMAP plots of snRNAseq from human (a) and mouse (b) adrenals depicting similarly diverse cell types including cortical and non-cortical cells. Expression patterns of WNT2B, ROR2, FZD3 and FZD6 projected over the UMAP projections from human (c), and mouse (d) adrenals.

e. Representative smISH images of WNT2B, FZD3, FZD6 and ROR2 expression in the adrenal cortex of human adrenals. Scale bar: 25μm

f. Representative smISH images of Fzd3, Fzd6 and Ror2 expression in the adrenal cortex of mouse adrenals. Scale bar: 25μm