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2D presentation of pyridopyrimidine 5 with EGFR and CDK6 binding site versus Erlotinib and ligand PD0332991, respectively as references. (A) Binding of pyridopyrimidine 5 with EGFR, compared to Erlotinib binding, (B) Binding of pyridopyrimidine 5 with CDK6 versus the ligand PD0332991 binding.
