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Neutrophil degranulation is stimulated by LN sera. Neutrophils isolated from HDs were incubated with sera from 11 patients with LN and nine HDs. Degranulation was measured as plasma membrane expression of CD35 for secretory vesicles and CD66b for specific granules. Statistical analyses for comparison of more than two independent groups were performed by Kruskal–Wallis tests with post hoc–corrected Dunn tests and P values shown. Data are displayed as averages±SD.
