Table 1.
Participant demographics.
| Controls | AD patients | p-value | |
|---|---|---|---|
| Age | 64.00 ± 5.25 | 59.62 ± 7.59 | 0.0779 |
| Female sex | 11 (68.75%) | 8 (61.54%) | 0.7141 |
| White race | 15 (100.00%) | 12 (92.31%) | 0.4643 |
| Education | 18.0 (17.0–18.25) | 18.0 (14.0-18.0) | 0.2979 |
| Right handedness | 16 (100.00%) | 10 (76.92%) | 0.0783 |
| CDR | 0.0 (0.0–0.0) | 1.0 (0.5-1.0) | <0.0001 |
| CDRSOB | 0.0 (0.0–0.0) | 4.5 (4.0-5.0) | <0.0001 |
| MMSE | 30.0 (29.75–30.0) | 23.0 (22.0-24.0) | <0.0001 |
Abbreviations: AD, Alzheimer's disease; CDR, Clinical Dementia Rating; CDR-SOB, CDR Sum of Boxes; MMSE, Mini-Mental State examination.
The AD cohort included four patients with CDR = 0.5 and nine patients with CDR = 1; Values for age are mean ± SD.
Age ranges are 49.36–77.45 and 56.22–75.56, for Alzheimer's disease patients and control participants respectively. Statistical tests were unpaired t-tests for age, education, CDR, CDR-SOB, MMSE; Fisher Exact test was used for sex, race, and handedness. Race was self-reported; one control participant and 1 patient with AD withheld from reporting race. Scores on the MMSE range from 0 to 30, with higher scores denoting better cognitive function.