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. 2024 Aug 21;18:1424920. doi: 10.3389/fnhum.2024.1424920

Table 1.

Participant demographics.

Controls AD patients p-value
Age 64.00 ± 5.25 59.62 ± 7.59 0.0779
Female sex 11 (68.75%) 8 (61.54%) 0.7141
White race 15 (100.00%) 12 (92.31%) 0.4643
Education 18.0 (17.0–18.25) 18.0 (14.0-18.0) 0.2979
Right handedness 16 (100.00%) 10 (76.92%) 0.0783
CDR 0.0 (0.0–0.0) 1.0 (0.5-1.0) <0.0001
CDRSOB 0.0 (0.0–0.0) 4.5 (4.0-5.0) <0.0001
MMSE 30.0 (29.75–30.0) 23.0 (22.0-24.0) <0.0001

Abbreviations: AD, Alzheimer's disease; CDR, Clinical Dementia Rating; CDR-SOB, CDR Sum of Boxes; MMSE, Mini-Mental State examination.

The AD cohort included four patients with CDR = 0.5 and nine patients with CDR = 1; Values for age are mean ± SD.

Age ranges are 49.36–77.45 and 56.22–75.56, for Alzheimer's disease patients and control participants respectively. Statistical tests were unpaired t-tests for age, education, CDR, CDR-SOB, MMSE; Fisher Exact test was used for sex, race, and handedness. Race was self-reported; one control participant and 1 patient with AD withheld from reporting race. Scores on the MMSE range from 0 to 30, with higher scores denoting better cognitive function.