Table 7.
Treatment-related adverse events.
| Toxicity | Nab-paclitaxel (n=166) |
Docetaxel (n=59) | χ2 | P |
|---|---|---|---|---|
| Diarrhea | ||||
| 0 | 79 | 29 | 0.825 | 0.662 |
| 1~2 | 73 | 23 | ||
| 3~4 | 14 | 7 | ||
| Neutropenia | ||||
| 0 | 92 | 34 | 0.454 | 0.797 |
| 1~2 | 55 | 17 | ||
| 3~4 | 19 | 8 | ||
| Vomit | ||||
| 0 | 86 | 26 | 1.065 | 0.587 |
| 1~2 | 67 | 28 | ||
| 3~4 | 13 | 5 | ||
| Fatigue | ||||
| 0 | 52 | 24 | 3.739 | 0.154 |
| 1~2 | 80 | 29 | ||
| 3~4 | 34 | 6 | ||
| Dizziness | ||||
| 0 | 118 | 50 | 5.323 | 0.070 |
| 1~2 | 41 | 9 | ||
| 3~4 | 7 | 0 | ||
| Hectic fever | ||||
| 0 | 113 | 44 | 3.154 | 0.207 |
| 1~2 | 45 | 15 | ||
| 3~4 | 8 | 0 | ||
| Infusion-related reaction | ||||
| 0 | 154 | 54 | 2.442 | 0.295 |
| 1~2 | 9 | 5 | ||
| 3~4 | 3 | 0 | ||
| Decreased appetite | ||||
| 0 | 101 | 41 | 1.511 | 0.470 |
| 1~2 | 53 | 14 | ||
| 3~4 | 12 | 4 | ||
| Elevated AST | ||||
| 0 | 123 | 43 | 5.927 | 0.052 |
| 1~2 | 23 | 14 | ||
| 3~4 | 20 | 2 | ||
| Elevated ALT | ||||
| 0 | 127 | 35 | 7.762 | 0.021 |
| 1~2 | 26 | 19 | ||
| 3~4 | 13 | 5 | ||
| Anemia | ||||
| 0 | 136 | 43 | 2.730 | 0.255 |
| 1~2 | 25 | 12 | ||
| 3~4 | 5 | 4 | ||
| Allergy | ||||
| 0 | 113 | 18 | 44.142 | 0.000 |
| 1~2 | 48 | 33 | ||
| 3~4 | 5 | 8 | ||
| Peripheral sensory neuropathy | ||||
| 0 | 69 | 36 | 6.713 | 0.035 |
| 1~2 | 75 | 17 | ||
| 3~4 | 22 | 6 | ||
| Oral mucositis | ||||
| 0 | 92 | 30 | 4.190 | 0.123 |
| 1~2 | 50 | 25 | ||
| 3~4 | 24 | 4 | ||
| Insomnia | ||||
| 0 | 120 | 54 | 9.648 | 0.008 |
| 1~2 | 29 | 2 | ||
| 3~4 | 17 | 3 | ||
| Difculty breathing | ||||
| 0 | 144 | 51 | 4.729 | 0.094 |
| 1~2 | 13 | 8 | ||
| 3~4 | 9 | 0 | ||