Fig. 4. Disease stage comparison of network modeling.
A Correlation of cortical thickness abnormality in SCZ to node- level functional (upper) and structural (lower) maps of degree centrality (all r > 0.23, pspin< 0.05). Color code indicates first- episode, early disease stage, and chronic disease stage from brighter to darker colors. B SCZ epicenter mapping (for details, see Fig. 2). Divergent (unique) epicenters are only significant in one of three disease stages with color indicating the corresponding disease stage. Convergent epicenters are significant in all three disease stages (pspin < 0.05). Subgroups of disease stages are defined by duration of illness: first-episode psychosis (<1 month); early disease stage (>1 month but <2 years); chronic disease stage (>20 years). FEP First episode psychosis.