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. 2024 Sep 3;14:20508. doi: 10.1038/s41598-024-71446-8

Fig. 3.

Fig. 3

Assessment of TTR variant stability. The residual TTR tetramer percentage (%) after urea-induced denaturation of recombinant wild-type TTR, recombinant T119M TTR, recombinant V30M TTR, and recombinant V122I TTR (A). Comparison of the residual TTR tetramer formation ratio of TTRs after 7.2 mol/L urea treatment (B). Values are expressed as means ± SDs (n = 6). **p < 0.01, ***p < 0.001. Data were analyzed by one-way ANOVA with Dunnett’s multiple comparisons test. TTR, transthyretin; WT, wild-type.