Table 6.

Published population PK models used to simulate steady-state quasi-continuous individual FIX activity levels as a function of time.

	rIX-FP	rFIX	rFIXFc	N9-GP
Published population and PK model characteristics
Source	Zhang et al.13	Suzuki et al.16	Diao et al.17	Collins et al.12
Number of patients	104	201	135	16*
Age range (years)	1–65	0–69	12–77	21–55*
PK model structure	2-compartment	2-compartment	3-compartment	2-compartment

*Values reported in Negrier et al.²⁷.

PK, pharmacokinetic.