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. 2024 Sep 3;14:20489. doi: 10.1038/s41598-024-68150-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Comparison of the occurrence of distant metastases and OS and PFS survival curves between the two groups of patients. (A) The disparity in distant metastasis between the low and high subgroups exhibits statistical significance (P < 0.001). (B) The mean OS for the low subgroup is 49 months, contrasting with 40 months for the high subgroup, both statistically significant (P < 0.05). (C) The mean PFS in the low subgroup spans 41 months, while the median PFS in the high subgroup stands at 27 months, both showing statistical significance (P < 0.05).