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. 2024 Sep 3;14:20489. doi: 10.1038/s41598-024-68150-y

Table 3.

Assessment of peripheral blood inflammation indexes in the two groups of patients.

Index metAstasis, n = 123 Non-metastasis, n = 201 P
WBC (× 109/L) 6.72 (5.7, 8.205) 6.21 (5.07, 7.51) 0.082
NEUT (× 109/L) 4.17 (3.175, 5.74) 3.655 (2.95, 4.81) 0.011
LYMP (× 109/L) 1.62 (1.255, 2.13) 1.835 (1.41, 2.2875) 0.09
PLT (× 109/L) 266 (211, 342) 253.5 (203.25, 326.25) 0.593
MON (× 109/L) 0.43 (0.31, 0.68) 0.37 (0.29, 0.52) 0.017
PLR 161.45 (121.665, 235.36) 139.04 (108.345, 183.04) 0.221
NLR 2.56 (1.66, 4) 1.975 (1.4925, 2.9725) 0.003
LWR 3.52 (2.5, 5.28) 4.945 (3.25, 6.7375) 0.002
NWR 0.64 (0.555, 0.74) 0.60 (0.51, 0.67) 0.014
SII 619.62 (464.755, 1216.465) 512.725 (363.35, 782.62) 0.007
SIAI 305.78 (172.635, 599.355) 202.23 (119.56, 346.8125) 0.002
dNLR 0.64 (0.555,0.74) 0.60 (0.51, 0.67) 0.049
MLR 0.28 (0.19, 0.40) 0.20 (0.15, 0.31) 0.002
NLPR 156.40 (124.71, 239.5) 153.305 (114.6925, 195.63) 0.157
SIRI 1.17 (0.62, 2.21) 0.75 (0.49,1.25)  < 0.001
PNI 51.75 (46.8, 56) 55.175 (50.6625, 58.6625)  < 0.001
ALI 391.17 (235.4, 584.455) 536.855 (355.1225, 731.4725)  < 0.001
INF-γ (Pg/ml) 48.2 (36.45, 68.75) 46.65 (37.625, 64) 0.99
TNF-α (Pg/ml) 30.9 (27.9, 35.6) 31.3 (28.9, 34.9) 0.386
IL-10 (Pg/ml) 12.3 (10.15, 16.05) 11.6 (9.1, 13.9) 0.003
IL-6 (Pg/ml) 14 (11.1, 18.6) 13.25 (10.9, 16.375) 0.049
IL-4 (Pg/ml) 26.4 (22.5, 37.25) 25.9 (21.9, 31) 0.117
IL-2 (Pg/ml) 20.6 (17.55, 23.45) 19.7 (18.1, 21.675) 0.189

The results revealed statistically significant differences between the two groups for NEUT (P = 0.011), MON (P = 0.017), NLR (P = 0.003), LWR (P = 0.002), NWR (P = 0.014), SII (P = 0.007), SIAI (P = 0.002), dNLR (P = 0.049), MLR (P = 0.002), SIRI (P < 0.001), PNI (P < 0.001), ALI (P < 0.001), IL10 (P = 0.003), and IL6 (P = 0.049).

Significant values are in [bold].