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. 2024 Sep 3;14:20455. doi: 10.1038/s41598-024-70992-5

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

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Fig. 1 — Characterization of rheological properties and DOX elution. (A) G’ (storage modulus) and G” (loss of modulus) during temperature ramp from 0 to 37 °C of POL gel with iodixanol (40 mg/mL of iodine), and DOX (10 mg/mL) containing 0%, 0.01%, 0.1%, and 1% MBs. (B) Viscoelastic properties of POL gel containing iodixanol and DOX: G’, G”, and ƞ* for 0%, 0.01%, 0.1%, and 1% MBs. (C) Thixotropic behavior of POL gel with iodixanol and DOX containing 0.01% MBs over time depicting ƞ* before strain (light tan), during strain (red), and after strain (green). (D) G’ and G” viscoelastic properties of POL with iodixanol and DOX containing 0.01% MBs over frequency domain. (E) G’ and G” viscoelastic properties of POL with iodixanol and DOX containing 0.01% MBs over oscillation strain sweep. (F) DOX elution for POL with 10 mg/mL DOX and iodixanol containing 0%, 0.01%, 0.1%, and 1% MBs. ***p < 0.001, ****p < 0.0001, from one-way ANOVA statistical test. Error bars represent means and standard deviations. n = 3 for all measurements.