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. 2024 Sep 3;10:79. doi: 10.1038/s41522-024-00558-w

Fig. 4. Host defense against alcohol-associated bacterial pneumonia requires activated AhR and decreased TGF-b signaling.

Fig. 4

A Overview of the dosing regimen for animals treated with indole, recombinant TGF-β1, anti-TGF-β1, and the AhR antagonist CH223191. K. pneumoniae (B) lung and (C) splenic burden at 48 h. post-infection in binge-on-chronic alcohol-treated mice. p values are indicated in the figure by one‐way ANOVA with Sidak’s multiple comparison. N = 6–14 mice/group derived from 2 independent experiments.