Table 4.
Incidence rate of MAT events, stratified by age: crude incidence rate of MAT events in BM donors by age
| Age, years | 18-29 | 30-39 | 40-49 | 50+ |
|---|---|---|---|---|
| No. of donors | 2542 | 2186 | 1804 | 591 |
| Donor-years | 21 549 | 23 995 | 20 671 | 6428 |
| Myeloid | ||||
| Donor-years | 21 549 | 23 993 | 20 671 | 6428 |
| Events | 0 | 2 | 1 | 0 |
| Crude rate∗ | 0.00 | 8.34 | 4.84 | 0.00 |
| 95% CI | N/A | 2.08-33.33 | 0.68-34.34 | N/A |
| Lymphoid | ||||
| Donor-years | 21 547 | 23 985 | 20 653 | 6387 |
| Events | 1 | 3 | 2 | 4 |
| Crude rate∗ | 4.64 | 12.51 | 9.68 | 62.63 |
| 95% CI | 0.65-32.95 | 4.03-38.78 | 2.42-38.72 | 23.51-166.8 |
| Other malignancies | ||||
| Donor-years | 21 305 | 23 513 | 19 786 | 5949 |
| Events | 41 | 91 | 156 | 80 |
| Crude rate∗ | 192.44 | 387.02 | 788.45 | 1344.74 |
| 95% CI | 141.7-261.3 | 315.3-475.1 | 674.4-921.8 | 1081.7-1671.8 |
| Autoimmune | ||||
| Donor-years | 21 194 | 23 611 | 20 208 | 6257 |
| Events | 73 | 71 | 84 | 34 |
| Crude rate∗ | 344.44 | 300.71 | 415.67 | 543.43 |
| 95% CI | 273.9-433.1 | 238.4-379.3 | 335.8-514.6 | 388.6-759.8 |
| Thrombosis | ||||
| Donor-years | 21 460 | 23 871 | 20 506 | 6335 |
| Events | 20 | 27 | 34 | 14 |
| Crude rate∗ | 93.19 | 113.11 | 165.80 | 221.01 |
| 95% CI | 60.14-144.4 | 77.58-164.9 | 118.5-232.0 | 131.0-372.9 |
N/A, not applicable; CI, Confidence Interval.
∗
Incidence rate per 100 000 person-years.