Table 6.
Age-adjusted incidence rates of malignancies in donors compared with the US general population: PBSC donors vs US general population (SEER)
| Outcomes | PBSC donors |
US general population (SEER) |
Rate ratio (95% CI) | P value | ||||
|---|---|---|---|---|---|---|---|---|
| Person, -years | No. of events | Incidence rate∗ (95% CI) | Person-years | No. of events | Incidence rate∗ (95% CI) | |||
| Myeloid | 118 712 | 3 | 2.53 (0.82-7.84) | 2 211 987 365 | 396 134 | 17.91 (17.85-17.96) | 0.14 (0.05-0.44) | <.001† |
| Lymphoid | 118 649 | 17 | 14.33 (8.91-23.05) | 2 211 987 365 | 746 740 | 33.76 (33.68-33.84) | 0.42 (0.26-0.68) | <.001† |
| Other malignancies | 116 213 | 535 | 460.36 (423.0-501.0) | 2 211 987 365 | 12 569 821 | 568.3 (567.9-568.6) | 0.81 (0.74-0.88) | <.001† |
CI, Confidence Interval
∗
Age-adjusted incidence rate per 100 000 person-years.
†
Result is statistically significant (P < .05).