Table 7.
Age-adjusted incidence rates of malignancies in donors compared with the US general population: BM donors vs US general population (SEER)
| Outcomes | BM donors |
US general population (SEER) |
Rate ratio (95% CI) | P value | ||||
|---|---|---|---|---|---|---|---|---|
| Person- years | No. of events | Incidence rate∗ (95% CI) | Person-years | No. of events | Incidence rate∗ (95% CI) | |||
| Myeloid | 72 641 | 3 | 4.13 (1.33-12.8) | 2 211 987 365 | 396 134 | 17.91 (17.85-17.96) | 0.23 (0.07-0.72) | .011† |
| Lymphoid | 72 572 | 10 | 13.78 (7.41-25.61) | 2 211 987 365 | 746 740 | 33.76 (33.68-33.84) | 0.41 (0.22-0.76) | .005† |
| Other malignancies | 70 553 | 368 | 521.59 (471.1-577.6) | 2 211 987 365 | 12 569 821 | 568.3 (567.9-568.6) | 0.92 (0.83-1.02) | .100 |
∗
Age-adjusted incidence rate per 100 000 person-years.
†
Result is statistically significant (P < .05).