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ΔTGM1 3D SEs resembling LI skin hallmarks and architecture
Histological analysis (H&E) and immunostaining of TG1 substrates (involucrin, LEKTI, and loricrin) and keratin 10 on 3D SEs from wild-type, ΔTGM1, or SINγ-RV-TGM1-transduced keratinocytes. DAPI (blue) stains nuclei. A dotted line marks the epidermal-dermal junction. Scale bars, 20 μm.
