TABLE 2.
Treatment day | Time from injection (min) | |||||||
---|---|---|---|---|---|---|---|---|
−20 | +30 | +60 | +90 | + 120 | + 150 | +240 | +360 | |
Saline | ||||||||
Mean | 7.1 | 7.1 | 7.0 | 7.0 | 6.9 | 7.0 | 7.2 | 7.1 |
SEM | 0.5 | 0.4 | 0.4 | 0.5 | 0.4 | 0.4 | 0.4 | 0.5 |
Naltrexone 10 mg | ||||||||
Mean | 6.8 | 6.6 | 6.7 | 6.6 | 6.8 | 6.6 | 6.9 | 7.0 |
SEM | 0.5 | 0.4 | 0.4 | 0.5 | 0.4 | 0.4 | 0.4 | 0.5 |
Nalmefene 10 mg | ||||||||
Mean | 6.9 | 6.6 | 6.9 | 6.9 | 6.7 | 6.7 | 7.0 | 7.1 |
SEM | 0.4 | 0.4 | 0.4 | 0.4 | 0.5 | 0.5 | 0.5 | 0.4 |
Abbreviations: ANOVA, analysis of variance; SEM, standard error of the mean.
VAS scale was 10 cm long, labelled as “terrible” on the left and “terrific” on the right. Data are presented in cm.
A two-way repeated measures ANOVA (treatment day × time from injection) was non-significant (see Results).