Fig. 3.

Irp2-null mice exhibit a deficit in somatosensory perception

WT and Irp2^−/− mice tested on a hot (A–B) and cold (C–D) plate assays. Irp2^−/− mice had a significant decrease in number of hind-paw licks (A) and increase in latency to first hind-paw lick (B). Irp2^−/− mice had a significant decrease in the number of jumps (C) and a significant increase in latency to first jump (D). In the absence of an event, latency was recorded at 30 s (dotted line). **p < 0.01, ***p < 0.001.