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. 2024 Aug 13;68(9):e00863-24. doi: 10.1128/aac.00863-24

TABLE 1.

Definitions of pharmacokinetic model parameters

Parameter (units) Definition
Cl (L/h) Clearance rate of the drug
Vc (L) Central compartment volume
Q (L/h) Inter-compartmental clearance rate
Vp (L) Peripheral compartment volume
ka (/h) Absorption rate