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Population parameters (θ) and feasible lower (b) and upper (a) prior bounds for each parameter in the first-order absorption two-compartment pharmacokinetic model for cipargamin
| Parameter (units) | θ | [b, a] |
|---|---|---|
| Cl (L/h) | 5.5 | [2.75, 11] |
| Vc (L) | 64.4 | [32.2, 128.8] |
| Q (L/h) | 12.9 | [6.45, 25.8] |
| Vp (L) | 107 | [53.5, 214] |
| ka (/h) | 0.919 | [0.460, 1.838] |
