TABLE 5.
Population parameters (θ) and feasible lower (b) and upper (a) prior bounds for each parameter in the pharmacodynamic model
| Parameter (units) | θ | [b, a] |
|---|---|---|
| ipl (total #) | 1800 | [1500, 2100] |
| µipl (h) | 2 | [1, 24] |
| σipl (h) | 3 | [1, 14] |
| PMF | 13 | [5, 50] |
| Emax (% killed/h) | 0.23 | [0.05, 1] |
| EC50 (ng/mL) | 15.1 | [0.5, 30] |
| γ | 5 | [1, 10] |