Table 2.
Mutation frequency (percentage) within two time points available for Patient B. Mutations were selected considering a minor allele frequency > 5% between at least two samples
| Gene | Mutation | Day 1 (%) | day8 6 (%) |
|---|---|---|---|
| E | T30I | 0 | 82.1 |
| M | Q19E | 43.9 | 90.6 |
| N | A182V | 0 | 99.3 |
| nsp13 | Y324C | 0 | 99.7 |
| nsp9 | T35I | 0 | 99.4 |
| RdRP | F694Y | 18.4 | 0.0 |
| S | Y144del | 0 | 99.6 |
| S | P217H | 0 | 99.7 |
| S | S256L | 99.5 | 0 |
| S | F374del | 0 | 91.2 |
| S | S375del | 0 | 99.9 |
| S | T376del | 0 | 99.8 |
| S | N440K | 0 | 100 |
| S | R408S | 24.7 | 32.9 |
| S | K444N | 0 | 100 |
| S | L455F | 0 | 100 |
| S | P463R | 10 | 0 |
| S | V642G | 0 | 99.6 |
| S | S1147L | 99.6 | 0 |
| S | D1153Y | 0 | 99.8 |
The data analysis led to the observation of different behaviors in terms of the presence or absence of mutations